Molecular Subtypes and Genomic Profile of Primary Central Nervous System Lymphoma
نویسندگان
چکیده
منابع مشابه
primary central nervous system lymphoma
objective primary central nervous system lymphoma (pcnsl) is an extremely rare condition in childhood. we report the first case of pcnsl in a child in iran. clinical presentation a nine-year-old boy was referred to mofid hospital with the history of headache of four months and seizure of 2 months duration. magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-pa...
متن کاملPrimary Central Nervous System Lymphoma
Primary central nervous system lymphoma (PCNSL) is an aggressive non‐Hodgkin Lymphoma, most frequently diffuse large B‐cell lymphoma in immunocompetent patients, which is confined to the central nervous system.[1] In the past two decades, its incidence has been steadily increasing. However, differential diagnosis, such as demyelinating disease, could be a challenge particularly in patients with...
متن کاملPrimary central nervous system lymphoma.
Primary lymphoma of the central nervous system (CNS), including reticulum cell sarcoma, microglioma, and histiocytic lymphoma, represents less than 1% of all primary brain tumors. In the last 10 years, this tumor has tripled in frequency in the nonimmunosuppressed population. By 1991, the tumor will be the most common neurological neoplasm by virtue of the increase in sporadic occurrence and in...
متن کاملPrimary central nervous system lymphoma.
Primary central nervous system (CNS) lymphoma is an unusual but increasingly frequent brain tumor being identified by neurologists. Considerable improvements in survival have been accomplished by the addition of chemotherapy to cranial radiotherapy. In addition, many patients achieve substantial disease free survival with chemotherapy alone, and survival is superior to radiotherapy alone. Curre...
متن کاملPrimary central nervous system lymphoma.
Primary CNS lymphomas (PCNSL) represent a subgroup of malignancies with specific characteristics, aggressive course, and unsatisfactory outcome in contrast with other lymphomas comparable for tumour burden and/or histological type. Despite a high chemo- and radiosensitivity, remissions are frequently shortlasting, mainly because the blood brain-barrier limits the access of many drugs to the CNS...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2019
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/nlz125